OK, the other way to do this requires you to open something as an external application. Word will do this but it is notoriously cranky.
For THIS approach, you will need to look up the following topics
In Access, creating an application (and the help files specifically include an example or two on doing exactly that step).
In Word, you need to open the help files on "Using VBA" and browse the heck out of the topic. You want to find the Paragraphs collection and get a list of the methods available under that collection. One of them will be a Find method. (Or maybe FindText)
Basically, using THIS approach, from a VBA routine you would ...
Create a Word application
Open the targeted file from within that application.
Specify a find and replace operation as a method of the paragraphs collection (I think...) I forget whether the .Find automagically has a replace option or whether .FindAndReplace is a separate method of Paragraphs.
When you have done the last find and replace, save the file and close it. At this point you must be EXTREMELY CAREFUL in what you specify as a file format. If you get it wrong, it won't be text anymore. (Gee, Toto - I don't think we're in Kansas any more...)
Close the application.
You're done.
Failure to close the app or the file will result in sloppy shutdowns and an eventual "out of memory" error in something (not necessarily Access).
Now, you will note that I have not given you the code for this. I am not at the place where I did that a couple of years ago and I'm running from memory. My notes are packed away at the moment. So while I have actually done a more complex version of this that included statistical analysis of certain factors in the file, I'm not about to give you half-remembered detail-level code snippets.
The reason this is so much trouble is that you are working from the wrong end of the control chain. To do a find-and-replace as a monolithic action via programming, you MUST work in an editor that exposes its components via the Component Object Model (COM) - or whatever term Bill Gates likes for this concept these days. This used to be called ActiveX, though there is more to this term than just pushing the buttons on another application. Which is why I cannot just tell you to run Notepad. I don't think Notepad exposes itself this way. Not sure, but Wordpad might not, either. Which leaves you with Word, the crankiest word processor in existence.
The thing that bothers me about this approach is that it would be FAR easier, even for a small bunch of files, to just do this by hand. This task is so complex to achieve such a simple result that I doubt it would pay off unless you had literally HUNDREDS of files to do this way.
The other method I suggested earlier is easier - using VBA to pass the characters of a file one character at a time UNLESS the character is one of the quoting characters. You are obviously not very experienced with text management in order to even ask the question. Well, I've been doing this and other types of text manipulation for a little over 29 years, off and on. What you asked is not as east to do as it is to say. Not by a long shot. And you are choosing the most complex method by wanting to do a find and replace through a program interface. Trust me, you would do better choosing any other method first.
Oh the other hand, I would do you a disservice if I didn't at least point the way, which I have done. And you DO need to gain experience. You know what "experience" is, don't you? It is the ability to recognize your mistakes when you make them again. (with apologies to Ambrose Bierce...)