I've had many times where the Run button is grayed out (in those moments, I haven't tried to notice about other menus/buttons, but probably they were too?) .... In these instances, it is a matter of Access being very slow. Sometimes it has taken anywhere from 10 seconds to 2 minutes for the screen (which doesn't appear to be frozen, but apparently is somehow still working), to enable all the options. Not sure if this is your case or not.