Ahh. For future reference, they are called quotation-marks, or, in technical context, double-quotes. Also, removing them from a CSV file is not always a good idea, because many programs that read CSV files use double-quotes as text-qualifiers. (Text-qualifier: a character that is used to identify both the beginning and the end of a text entry).
Can you give us more background on what you are attempting to accomplish, the application environment, and some sample-data, so that we may better advise you as to the best method of dealing with the double-quotes?