The only input I have is that with any product that is imbibed once a corporation gets there hands on it the quality, safety and desirability of it typically goes down in the name of reaching a bottom line where output is through the roof and cost is driven as far down as possible.
I think it would be great for a short period of time until the unavoidable "big marijuana" moves in and lobbies for laws to prevent people from growing their own because it's hurting their right to grow and sell it.
I also can't wait to see what new and terrible chemicals they begin lacing it (a la tobacco) with to increase potency, cheaply.
I voted yes, but the externalities that would accompany it would eventually outweigh the good.
*EDIT* Oh, and let us not forget that at one time Opium was prescribed as treatment for alcoholism because it was considered socially acceptable to lounge lethargically instead of angrily beating members of your family.