That is not one table, that is at least eight or nine tables and many relationships.
Every time you have a lookup, that implies that the lookup is part of a separate table that holds only the definitions you need for that lookup.
Also, the special characters in some of those field names FIRST cannot be there, SECOND make me think that some of the items are actually conditions that can be part of a QUERY and therefore not stored. THIRD, I strongly concur with the other posters that you need to look up the topic of "Database Normalization".
You can find help in the Access Help arena using "Normalization."
You can find a decent starter article at
www.wikipedia.org using keywords "Database Normalization"
You can use your favorite flavor of search engine for "Database Normalization" - but in this case, you'll get so many hits that you need to know the best possible filters. Don't bother to try to do a filtration search, just set up your browser to show you the hosting domain name and only look at entries from the .EDU (education) domain. Limit yourself to colleges and universities that you've heard of and know by reputation. Read the articles until you have read two non-trivial articles in a row that didn't tell you anything you didn't already know. A "non-trivial" article is one of at least two or three full printed pages and probably should be more than that.
Revisit your fields. Using the normalization rules, you want to look for a couple of ways to filter things.
First simple filter: Do I have enough information already elsewhere in the table to recompute this item on-the-fly? If so, then it belongs ONLY in a query, never in a table. (If the information changes over time, that's a special case.)
Second simple filter: Is the information something that will (or at least is likely to) be used for looking up something for another field? If so, you have candidates for splitting tables.
Your goal: NEVER EVER more than 255 fields per single table. And even that is likely too many. Normalize to a level of at least 3rd normal form.
Search this forum for articles on database design, some of which include a how-to for the analysis of the entities you will need to track. (I know they exist; I wrote some of them. Others of my esteemed forum colleagues have also written nice starter articles.)
Your problem is going to be totally intractible UNTIL you normalize it and break it up into meaningful and usable entities. As a starting point, why did your spreadsheet have several tabs with multiple fields listed on each? (That's rhetorical: Answer - because you already realized those entities on tab X were different in nature from the entities on tab Y.) As a first approximation, I strongly suspect you will have no fewer tables than the number of distinct tabs you had on your spreadsheet. The 255-field limit applies to each table individually. You certainly can have more than 255 fields in a database. Just not all in one table.