don't think your registry entry is correct. You said you are using 2010 - that is 14.0, not 12.0. Also I don't think path is correct - should just be a path, no file.
suggest on your development machine open access the select file>options>trust centre. Then select trust centre settings. Then click on trusted locations and choose a path and save.
When done, open the registry and see what has been entered
Cj,
You are correct about the 12.0, I just didn't change that number when I sent it to you. I was always using 14.0. Either way I was able to get rid of the warning. I had the path directed to the DB, not the just the folder where it is stored. I no longer have the warning and everything is working as it should. Thank for your help along with everyone else! It's awesome that if I have a problem people like you are willing to help.